Knee-OA studies use 500–1,500 mg/day curcuminoids for 8–12 weeks, with major formulation differences
Reviewed · Published
Turmeric / curcumin
A turmeric polyphenol; enhanced-absorption formulations may also increase interactions and harms.
Established functions
- A turmeric polyphenol; enhanced-absorption formulations may also increase interactions and harms.
Dietary sources
- turmeric
- curry powder
Claims and evidence
Claims that Turmeric / curcumin alone prevents or treats disease, or invariably improves health without deficiency, are unsupported.
Japanese reference amounts
- Japanese adults (age and sex as specified): No Japanese DRI established
Amounts studied
- Knee-OA studies use 500–1,500 mg/day curcuminoids for 8–12 weeks, with major formulation differences
Tolerable upper limits
- No UL; liver injury has been reported with enhanced-bioavailability products
Forms and bioavailability
Supplement forms: standardized curcuminoids, phospholipid or piperine-enhanced
- Piperine and lipid complexes increase exposure and may also increase medicine interactions.
Safety and interactions
Adverse effects
- gastrointestinal symptoms
- biliary pain
- liver injury
- bleeding
Medicine and nutrient interactions
- anticoagulants, diabetes medicines, piperine-mediated metabolism inhibition
Contraindications and cautions
- Avoid high doses with gallstones or biliary obstruction, liver disease, before surgery, or in pregnancy.
Practical selection
- Compare Turmeric / curcumin amount per serving, form, allergens, and batch testing; prefer a single-ingredient product suited to the intended use.
Sources and review
- Turmeric: usefulness and safetyNational Center for Complementary and Integrative Health
Daiki Minaki (editorial and evidence review) ·
Frequently asked questions
How is Turmeric / curcumin different from its broader supplement category?
A turmeric polyphenol; enhanced-absorption formulations may also increase interactions and harms. Compare its named form and amount rather than assuming every category product supplies it.
View detailsWhat safety detail matters specifically for Turmeric / curcumin?
anticoagulants, diabetes medicines, piperine-mediated metabolism inhibition Avoid high doses with gallstones or biliary obstruction, liver disease, before surgery, or in pregnancy.
View details